 http://ijib.classicrus.com/ ISSN: 0973-8363 Special Issue: BBB10 |    |
| IJIB 2009, 8(1), 1-6 |
 Wound healing activity of Cassia occidentalis L. in albino Wistar rats
Sheeba M, Emmanuel S, Revathi K, Ignacimuthu S The wound healing property of methanolic crude extract of Cassia occidentalis L. leaves and a pure compound Chrysophanol isolated from it was evaluated in excision, incision and dead space wound models. The parameters studied included rate of wound contraction and the [Abstract] | [PDF] |
| IJIB 2009, 8(1), 19-24 |
 Comparison in motional properties of Staphylococcus aureus exfoliative toxins A and B as revealed by their MD simulationMondal UK, Sen A, Bothra AK Exfoliative (epidermolytic) toxins (ETs) of Staphylococcus aureus can cause severe and life threatening illness in extremely premature neonates. Two serologically distinct forms of exfoliative toxin exist and have been designated as ETA and ETB. To understand the motional properties and mode [Abstract] | [PDF] |
| IJIB 2009, 8(1), 37-42 |
 PPRESearch: Peroxisome Proliferator Activator Element Search DatabaseVenkatachalam G, Sakharkar MK, Kumar AP, Clement MV Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors involved in processes such as angiogenesis, cell cycle, apoptosis, and lipid metabolism thereby having a significant effect on cell fate and cell metabolism. After activation, PPARs [Abstract] | [PDF] |
| IJIB 2009, 6(1), 27-32 |
 Biochemical characterization of gamma-aminobutyric acid (GABA):pyruvate transaminase during rice leaf senescenceAnsari MI, Chen SG Senescence-associated genes (SAGs) are up-regulated during plant senescence and may have been implicated in encoding enzymes involved in metabolism of senescence tissues. The gene Osl2 (GABA:pyruvate-transaminase) which is upregulated during leaf senescence in rice (Oryza sativa) was [Abstract] | [PDF] |
| IJIB 2009, 5(1), 9-12 |
 Indirect Immunofluorescence assay, Particle Agglutination and ELISA for the detection of HIV 1Kiptoo MK, Ng’ang’a ZW, Mpoke SS, Osman S, Mwangi A, Songok EM Screening of blood and blood products for
human immunodeficiency virus (HIV) is routinely performed using the
enzyme-linked immunosorbent assay (ELISA), and the results confirmed by western
[Abstract] | [PDF] |
| IJIB 2009, 5(1), 13-19 |
 3D-QSAR studies of xanthone derivatives as human alpha glucosidase inhibitorsSaqib U, Siddiqi MI Three-dimensional quantitative structure activity relationship (3D-QSAR) analyses were carried out on a set of 42 xanthone derivatives in order to understand their anti-alpha glucosidic activities. The studies include Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA).. . . [Abstract] | [PDF] |
| IJIB 2009, 5(1), 1-8 |
 Differential dynamics and stability of lamin A rod domain mutantsTripathi K, Muralikrishna B, Parnaik VK Mutations in the human lamin A gene give rise to highly debilitating diseases termed laminopathies. Laminopathic cells harboring certain mutations in lamin A display aberrant nuclear morphology due to abnormal lamina assembly. To understand the molecular mechanisms involved in these processes, we have studied the dynamics and stability of GFP-tagged lamin A.. . . [Abstract] | [PDF] |
| IJIB 2008, 4(1), 1-8 |
 Genetic and pharmacological interaction network of targets and drugsSakharkar MK, Sakharkar KR Accumulated knowledge on genomic information, systems biology, and disease mechanisms provide an unprecedented opportunity to elucidate the genetic basis of diseases, and to discover new and novel therapeutic targets from genomic data. With hundreds to a few thousand potential targets available in the human genome alone, and the rise in the role of multi-drugtherapies for complex diseases, . . . [Abstract] | [PDF] |
| IJIB 2009, 5(1), 49-57 |
 S29 ribosomal protein induces mitochondria mediated apoptosis of Hep2 cells via the activation of p38 MAPK and JNK signalingSaini N, Balhara J, Adlakha YK, Singh N Multifunctionality of proteins is one of the mechanisms accounting for the complexity of interactome networks in higher eukaryotes. Reports in the literature suggest that during oncogenesis and other pathologic conditions many proteins perform additional functions without changes in three . . . [Abstract] | [PDF] |